Pyoderma gangrenosum (PG) is a chronic, inflammatory skin condition characterized by painful, rapidly progressing ulcers. They can start as blisters (bullae), small inflamed pus-filled sores (pustules), orlarge open sores (ulcers). These ulcers typically have undermined (overhanging) borders and a violaceous (purplish) hue. PG can occur anywhere on the body but is often found on the legs. It is associated with various underlying systemic diseases, such as inflammatory bowel disease, rheumatoid arthritis, and hematologic malignancies. Treatment typically involves immunosuppressive medications and wound care management.