Dermatofibrosarcoma Protuberans

Dermatofibrosarcoma Protuberans

Dermatofibrosarcoma protuberans (DFSP) is a rare type of locally aggressive skin cancer. It originates from connective tissue cells in the dermis layer of the skin. It can show up in existing scars, vaccination sites, or tattoos. DFSP often presents as an asymptomatic, hardened plaque that slowly grows over months to years. As the tumor progresses, it becomes elevated, firm, and nodular. It is most commonly observed in individualsaged between 20 and 40, frequently originating from the trunk but can also occur in locations such as the lower extremities, upper extremities, head, and neck. Diagnosis is established through skin biopsy. While metastasis is uncommon, local recurrence rates are notably high. The optimal treatment for localized DFSP is complete excision with wide margins or Mohs. To reduce the local recurrence rate, wider margins (5 cm) are recommended.

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Due to high recurrence rates, the lesion is excised with wide margins.

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